(2S)-2-[[[[(1R,2R)-2-Aminocyclohexyl]amino]thioxomethyl]amino]-N,3,3-trimethyl-N-(phenylmethyl)butanamide, 98%, (99% ee),(S)-2-[[(1R,2R)-2-氨基环己基]硫脲基]-N-苄基-N,3,3-三甲基丁酰胺 , 98%, (99% ee)
(S)-2-[[(1R,2R)-2-氨基环己基]硫脲基]-N-苄基-N,3,3-三甲基丁酰胺 , 98%, (99% ee)
(2S)-2-[[[[(1R,2R)-2-Aminocyclohexyl]amino]thioxomethyl]amino]-N,3,3-trimethyl-N-(phenylmethyl)butanamide, 98%, (99% ee)
品牌: Strem
产品编号: 07-0956
分子式: C??H??N?OS
分子量: 390.60
纯度: 98%, (99% ee)
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基本信息

安全信息

化学和物理性质

产品描述

Technical Notes:

1.Conjugate Addition: Primary amine -thiourea derivative is an active and highly enantioselective catalyst for the conjugate addition of ketones to nitroalkenes.

2.Michael Addition: The asymmetric Michael addition of dioxindoles to ß-substituted nitroalkenes is reported. The bifunctional primary amine-thiourea, by means of a non-covalent-based mode of catalysis, secures

direct access to 3-substituted 3-hydroxyoxindole derivatives with high stereocontrol.

References:

1. J. Am. Chem. Soc., 2006, 128, 7170-7171.

2. Chem. Commun., 2012, 48, 3336-3338.

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