EGTA, AM , 90% , 是 EGTA 的膜渗透形式,可以被动地载入到细胞中产生细胞内的 EGTA, EGTA-AM 同时为 Ca2+ 螯合剂
EGTA, AM, 90%, a membrane permeable form of EGTA, can be passively loaded into cells to generate intracellular EGTA; EGTA-AM is also a Ca2+ chelator with slow chelating dynamics
分子式: C26H40N2O18
分子量: 668.60
纯度: 90%
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基本信息
MDL编码MFCD00077339 |
安全信息
存储条件Freezer -20℃ |
化学和物理性质
产品描述
产品描述
EGTA-AM is a membrane permeable form of EGTA, can be passively loaded into cells to generate intracellular EGTA; EGTA-AM is also a Ca2+ chelator with slow chelating dynamics.
体外研究
EGTA-AM (50 μM) markedly reduces the asynchronous excitatory postsynaptic currents (aEPSC) to 58.9 ± 8.1% of the control level, but only reduces the synchronous excitatory postsynaptic currents (EPSCs), measured as charge transfer produced by the stimulation train[1].
参考文献
[1]. Li MJ, et al. Cholinergic and glutamatergic transmission at synapses between pedunculopotine tegmental nucleus axonal terminals and A7 catecholamine cell group noradrenergic neurons in the rat. Neuropharmacology. 2016 Nov;110(Pt A):237-50
