NKL 22 , 98% , 是HDAC抑制剂
NKL 22, 98%, a HDAC inhibitor
分子式: C19H23N3O2
分子量: 325.40
纯度: 98%
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NKL 22 is a HDAC inhibitor. The value of IC 50 is 78 uM NKL 22 increase frataxin protein concentrations NKL 22 inhibitors increase FXN mRNA in FRDA lymphocytes. HDAC inhibitors act directly on FXN. [1]
靶点（IC50 & Targe）
HDAC
参考文献
[1]. D Herman et al. Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia. Nat Chem Biol, 2006 Oct, 2(10):551-8.
