应用

4-Fluoro-3-nitrobenzoic acid was used: as starting reagent in the preparation of novel benzimidazoles having antimycobacterial activity.in preparation of series of novel acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitors containing benzimidazole core structure.in preparation of bis(heterocyclic) skeletal precursors for the Pictet-Spengler reaction.in solid-phase synthesis of trisubstituted [1,3,5]triazino[1,2-a]benzimidazole-2,4(3H,10H)-diones.