Icaritin, 97%, potently inhibits proliferation of K562 cells (IC50 of 8 µM) and primary CML cells (IC50 of 13.4 µM for CML-CP and 18 µM for CML-BC). Icaritin can regulate MAPK/ERK/JNK and JAK2/STAT3 /AKT signalings,去水淫羊藿黄素 , 97% , 是 Epimedium Genusis 的异戊二烯类黄酮衍生物,有效抑制 K562 细胞 (IC50 为 8 µM) 和原代 CML 细胞 (对 CML-CP 的 IC50 值为 13.4 µM,对 CML-BC 的 IC50 值为 18 µM) 的增殖.Icaritin 可以调节 MAPK/ERK/JNK 和 JAK2/STAT3/AKT 信号传导,并具有增强成骨的作用
化学品安全技术说明书(SDS)
技术规格说明书(Specifications)
质检报告 (COA)
去水淫羊藿黄素 , 97% , 是 Epimedium Genusis 的异戊二烯类黄酮衍生物,有效抑制 K562 细胞 (IC50 为 8 µM) 和原代 CML 细胞 (对 CML-CP 的 IC50 值为 13.4 µM,对 CML-BC 的 IC50 值为 18 µM) 的增殖.Icaritin 可以调节 MAPK/ERK/JNK 和 JAK2/STAT3/AKT 信号传导,并具有增强成骨的作用
Icaritin, 97%, potently inhibits proliferation of K562 cells (IC50 of 8 µM) and primary CML cells (IC50 of 13.4 µM for CML-CP and 18 µM for CML-BC). Icaritin can regulate MAPK/ERK/JNK and JAK2/STAT3 /AKT signalings
品牌: J&K
产品编号: 1004425
分子式: C21H20O6
分子量: 368.38
纯度: 97%
包装库存价格
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基本信息

英文别名3,5,7-trihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)chromen-4-one
中文别名脱水淫羊藿素
n20D1.656
MDL编码MFCD00210516
Reaxys-RN (Beilstein)347627

安全信息

存储条件Store at 2-8℃
RTECSDJ3100870

化学和物理性质

MP239
BP582
FP206.7
Density1.359

产品描述

产品描述

Anhydroicaritin, a prenylated flavonoid natural product, is commonly recognized as one of the effective compounds of Epimedii Herba and exhibits a variety of biological activities, such as activation of cancer cell apoptosis and inhibition of growth, protection against beta amyloid-induced neurotoxicity, and promotion of neuronal and cardiac cellular differentiation. It is a potent inhibitor of transcription factor SREBPs.