百灵威电离/阳离子脂质领域新品

Ionizable lipids play a key role in the formulation of Lipid Nanoparticles (LNPs) used to deliver RNA therapeutics.

We have added three new products to our Ionizable and Cationic Lipid product suite.

• Lipid C24

Lipid C24 is an ionizable lipid used in lipid nanoparticle formulations for delivery of RNA. Key features:

• High binding and pseudoneutralizing antibodies

• Minimal injection site inflammation

品名：Lipid C24
产品编号：N-1024

• 93-O17S

93-O17S is a lipidoid used for generating lipid nanoparticles to deliver RNA, peptides, and nucleotides. Key features:

• Delivers Cre recombinase mRNA in mice

• Genome editing capabilities

• cGAMP delivery with potential as an in situ cancer vaccine

品名：93-O17S
产品编号：N-1175

• YSK05

YSK05 is an ionizable lipid used to make lipid nanoparticles for delivery of siRNA. YSK05 LNPs delivered siRNA to hepatocytes and demonstrated gene silencing after intravenous administration.

品名：YSK05
产品编号：N-1050

1. Echelon's Ionizable Lipids are are sold as Research Use Only (RUO).

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The COVID-19 pandemic has pushed ionizable lipids into the limelight with the rapid development of mRNA-based vaccines. A key part of this technology are the lipid nanoparticles (LNPs) used to deliver RNA.

mRNA-based vaccines are the culmination of two decades of research, and their incorporation of LNPs is a key factor in their success. There are countless applications for additional vaccines and therapeutics in the future.