百灵威向您推荐近期药物合成领域中国科学家发表的论文：

Pd(0)/Xantphos-Catalyzed Benzylic C(sp3)-O Arylation of Benzyl Heteroaryl Ethers: Reduction of Pd(II) to Pd(0) by Xantphos

Qingxue Ma, Fengdong Wang, Pengfei Zhang, Guoshuai Li, Yang Li, Xiaohua Xu, Zhong Jin

J Org Chem. 2024 Sep 20;89(18):13703-13708. doi: 10.1021/acs.joc.4c00966.

Radical Cascade Reaction of Heterocyclic Ketene Aminals with Thiocyanates Promoted by Visible Light: Synthesis of Functionalized Fused 2-Iminothiazolines

Shu Yang, Ting-Ting Guo, Jian-Bo Ma, Hui-Ting Jia, Jin Liu, Sheng-Jiao Yan

J Org Chem. 2024 Sep 20;89(18):13678-13690. doi: 10.1021/acs.joc.4c01899.

One-Pot Synthesis of Dihydrobenzo[a]fluorenes via Cascade C-H Annulation of Thiobenzamide with Alkynes

Xingwen Pu, Zhangyi Fu, Yudong Yang, Di Wu, Pengchi Deng, Jingbo Lan

J Org Chem. 2024 Sep 20;89(18):13110-13116. doi: 10.1021/acs.joc.4c01228.

Clock protein LHY targets SNAT1 and negatively regulates the biosynthesis of melatonin in Hypericum perforatum

Wen Zhou, Ru-Yi Xiao, Yi-Xiao Yang, Xue Wang, Dong-Hao Wang, Zhe-Zhi Wang

Sci Adv. 2024 Sep 20;10(38):eadq6505. doi: 10.1126/sciadv.adq6505.

Design, Synthesis, and Biological Evaluation of Lysine-Stapled Peptide Inhibitors of p53-MDM2/MDMX Interactions with Potent Antitumor Activity In Vivo

Lei Xu, Xin Fan, Yi He, Xuefeng Xia, Jinqiang Zhang

J Med Chem. 2024 Sep 19. doi: 10.1021/acs.jmedchem.4c01939.

Design, Synthesis, Anti-TMV Activity, and Structure-Activity Relationships of Seco-pregnane C21 Steroids and Their Derivatives

Ying Yan, Pan Tang, Siyu He, Xiangkai Kong, Rong-Hua Wang, Jing Shi, Tianyuan Zhang, Ying-Tong Di, Lei Tang, Xiao-Jiang Hao

J Agric Food Chem. 2024 Sep 18. doi: 10.1021/acs.jafc.4c03946.

Electrochemical promoted three-component reaction to unsymmetric thiosulfonates

Hong-Min Lin, Sai-Yan Ren, Fei-Hu Cui, Ying-Ming Pan, Hai-Tao Tang

Chem Commun (Camb). 2024 Sep 16;60(75):10394-10397. doi: 10.1039/d4cc03570d.

Design, Synthesis, and Insecticidal Activity of Isoxazoline Derivatives Incorporating an Acylhydrazine Moiety

Biaobiao Jiang, Di Feng, Jun Shi, Wei Wu, Yawen Dong, Hai Ren

J Agric Food Chem. 2024 Sep 16. doi: 10.1021/acs.jafc.4c04005.

Two-dimensional hydrophilic imprinted resin-graphene oxide composite for selective extraction and rapid determination of gibberellin traces in licorice samples

Mingwei Wang, Yanan Yuan, Yehong Han, Fengxia Qiao, Jinliang Li, Hongyuan Yan

Food Chem. 2024 Sep 15:452:139553. doi: 10.1016/j.foodchem.2024.139553.

Machine learning-based QSAR and LB-PaCS-MD guided design of SARS-CoV-2 main protease inhibitors

Borwornlak Toopradab, Wanting Xie, Lian Duan, Kowit Hengphasatporn, Ryuhei Harada, Silpsiri Sinsulpsiri, Yasuteru Shigeta, Liyi Shi, Phornphimon Maitarad, Thanyada Rungrotmongkol

Bioorg Med Chem Lett. 2024 Sep 15:110:129852. doi: 10.1016/j.bmcl.2024.129852.

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