百灵威向您推荐近期药物合成领域中国科学家发表的论文：

Two-dimensional hydrophilic imprinted resin-graphene oxide composite for selective extraction and rapid determination of gibberellin traces in licorice samples

Mingwei Wang, Yanan Yuan, Yehong Han, Fengxia Qiao, Jinliang Li, Hongyuan Yan

Food Chem. 2024 Sep 15:452:139553. doi: 10.1016/j.foodchem.2024.139553.

Machine learning-based QSAR and LB-PaCS-MD guided design of SARS-CoV-2 main protease inhibitors

Borwornlak Toopradab, Wanting Xie, Lian Duan, Kowit Hengphasatporn, Ryuhei Harada, Silpsiri Sinsulpsiri, Yasuteru Shigeta, Liyi Shi, Phornphimon Maitarad, Thanyada Rungrotmongkol

Bioorg Med Chem Lett. 2024 Sep 15:110:129852. doi: 10.1016/j.bmcl.2024.129852.

Synthesis and biological evaluation of novel penindolone derivatives as potential antiproliferative agents against SCLC in vitro

Jiaqi Lin, Yongqing Han, Bohan Li, Wenrui Gai, Zhengjie Wang, Qi Wang, Yueling Teng, Jing Li, Dehai Li

Bioorg Med Chem Lett. 2024 Sep 15:110:129877. doi: 10.1016/j.bmcl.2024.129877.

6-Methoxyldihydrochelerythrine Chloride Inhibiting Intra and Extracellular Drug-Resistant Bacteria

Li-Yu Bai, Zhao-Jie Wang, Qing-Yu Lu, Huan Huang, Yan-Yan Zhu, Yun-Li Zhao, Xiao-Dong Luo

ACS Infect Dis. 2024 Sep 13;10(9):3430-3439. doi: 10.1021/acsinfecdis.4c00571.

Design and Synthesis of 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic Acid Derivatives as PP5 Inhibitors To Reverse Temozolomide Resistance in Glioblastoma Multiforme

Zekun Li, Mochen Guo, Mingxiao Gu, Zhongtian Cai, Qiuyu Wu, Jia Yu, Meilun Tang, Chenxi He, Yuxuan Wang, Piaoyang Sun, Qidong You, Lei Wang

J Med Chem. 2024 Sep 12;67(17):15691-15710. doi: 10.1021/acs.jmedchem.4c01304.

Chemoenzymatic Synthesis of DNP-Functionalized FGFR1-Binding Peptides as Novel Peptidomimetic Immunotherapeutics for Treating Lung Cancer

Xiaohui Li, Haiyan Liu, Shengjie Ding, Ziyu Tian, Jia Song, Huayu Zhong, Luwei Fu, Xiaojun Cai, Fengyu Huang, Kun Wang, Lilong Dong, Weixin Zhao, Yuepiao Cai, Shijie Dai

J Med Chem. 2024 Sep 12;67(17):15373-15386. doi: 10.1021/acs.jmedchem.4c00967.

Design, Synthesis, and Biological Activity of Novel Quinone Derivatives as Potent STAT3 Inhibitors for Psoriasis Treatment

Ling Chen, Liuliu Wang, Jinlei Gao, Yuanzhu Xie, Xu Deng, Guang Tian, Mingjian Li, Zhongtai Sui, Cailin Luo, Li Liu, Xinyu Huang, Xinyu Zhu, Shuaiwen Zhu, Zhiyong Luo, Dayou Ma, Suyou Liu

J Med Chem. 2024 Sep 12;67(17):15438-15455. doi: 10.1021/acs.jmedchem.4c01055.

Design, Synthesis, and Biological Evaluation of 5-Amino-4-fluoro-1H-benzo[d]imidazole-6-carboxamide Derivatives as Novel and Potential MEK/RAF Complex Inhibitors Based on the 'Clamp' Strategy

Peng Wang, Yongting Yuan, Tao Yang, Yurong Zou, Minghai Tang, Ziyan Ma, Weichen Bo, Songhui Qin, Yong Chen, Tao Guo, Zhongning Guo, Jianhong Yang, Mingli Xiang, Lijuan Chen

J Med Chem. 2024 Sep 12;67(17):15246-15267. doi: 10.1021/acs.jmedchem.4c00860.

Design, Synthesis, and Evaluation of the Antitubercular Activity of 5-Phenyl Substituted-5, 6-dihydropyrido[2, 3-d]pyrimidine-4, 7(3H, 8H)-dione Compounds

Lianqi Sun, Shibo Kou, Bin Wang, Yongjian Wang, Jianzhou Meng, Tianfu Liu, Yuanyuan Ma, Jianyuan Zhao, Hong Yi, Shan Cen, Yu Lu, Zhuorong Li

J Med Chem. 2024 Sep 12;67(17):14927-14945. doi: 10.1021/acs.jmedchem.4c00441.

Synthesis and Photodynamic Activities of Pyridine- or Pyridinium-Substituted Aza-BODIPY Photosensitizers

Chang Liu, Chuan Liu, Xin Ji, Weili Zhao, Xiaochun Dong

J Med Chem. 2024 Sep 12;67(17):15908-15924. doi: 10.1021/acs.jmedchem.4c01641.

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