百灵威向您推荐近期药物合成领域中国科学家发表的论文：

Novel Hsp90-Targeting PROTACs: Enhanced synergy with cisplatin in combination therapy of cervical cancer

Jinsen Liang, Dandan Wang, Yijin Zhao, Yihe Wu, Xuelian Liu, Lilan Xin, Junhong Dai, Hang Ren, Hai-Bing Zhou, Hongbing Cai, Chune Dong

Eur J Med Chem. 2024 Sep 5:275:116572. doi: 10.1016/j.ejmech.2024.116572.

Discovery of autophagy-tethering compounds as potent NLRP3 degraders for IBD Immunotherapy

Kai Yin, Ziwen Zhang, Yanqing Mo, Hongyu Wu, Zhonglian Cao, Yongxing Xue, Mingrunlin Wang, Wei Guo, Li Feng, Chunchang Zhao, Xianfeng Gu

Eur J Med Chem. 2024 Sep 5:275:116581. doi: 10.1016/j.ejmech.2024.116581.

Design, synthesis and biological evaluation of 5-amino-1H-pyrazole-4-carboxamide derivatives as pan-FGFR covalent inhibitors

Wuqing Deng, Xiaojuan Chen, Hong Liang, Xiaojuan Song, Shuang Xiang, Jing Guo, Zhengchao Tu, Yang Zhou, Yongheng Chen, Xiaoyun Lu

Eur J Med Chem. 2024 Sep 5:275:116558. doi: 10.1016/j.ejmech.2024.116558.

Novel thiosemicarbazide-based β-carboline derivatives as α-glucosidase inhibitors: Synthesis and biological evaluation

Bingwen Liang, Di Xiao, Shao-Hua Wang, Xuetao Xu

Eur J Med Chem. 2024 Sep 5:275:116595. doi: 10.1016/j.ejmech.2024.116595.

Discovery and biological evaluation of biaryl acetamide derivatives as selective and in vivo active sphingosine kinase-2 inhibitors

Yanan Li, Gang Li, Yiming Wang, Longfei Li, Yali Song, Fei Cao, Kan Yang

Eur J Med Chem. 2024 Sep 5:275:116577. doi: 10.1016/j.ejmech.2024.116577.

Synthesis and biological evaluation of multimodal monoaminergic arylpiperazine derivatives with potential antidepressant profile

Jiefang Zheng, Liping Zhou, Xudong Gong, Feipu Yang, Jiaxin Cheng, Rui Ma, Chunhui Wu, Zhijian Xu, Weiliang Zhu, Yang He, Jingshan Shen

Eur J Med Chem. 2024 Sep 5:275:116564. doi: 10.1016/j.ejmech.2024.116564.

Design and synthesis of 6-C-alkyl-DMDP type nanomolar inhibitors of β-galactosidase and β-glucosidase based on broussonetine S and related derivatives

Feng-Teng Gao, Qing-Kun Wu, Ming Zhang, Yuna Shimadate, Gong Qian, Ying-Ying Song, Atsushi Kato, Yi-Xian Li, Yue-Mei Jia, George W J Fleet, Chu-Yi Yu

Eur J Med Chem. 2024 Sep 5:275:116570. doi: 10.1016/j.ejmech.2024.116570.

Design, synthesis, and biological evaluation of pyrido[2,3-d]pyrimidin-7(8H)-one derivatives as potent USP1 inhibitors

Hongrui Li, Ben-Jin Liu, Jiahao Xu, Shan-Shan Song, Ruixian Ba, Junjie Zhang, Xia-Juan Huan, Dun Wang, Ze-Hong Miao, Tongchao Liu, Jin-Xue He, Bing Xiong

Eur J Med Chem. 2024 Sep 5:275:116568. doi: 10.1016/j.ejmech.2024.116568.

Novel carbazole-oxadiazole derivatives as anti-α-glucosidase and anti-α-amylase agents: Design, synthesis, molecular docking, and biological evaluation

Shuang Luo, Li Zhao, Huining Peng, Zhiyun Peng, Guangcheng Wang

Eur J Med Chem. 2024 Sep 5:275:116600. doi: 10.1016/j.ejmech.2024.116600.

Corrigendum to 'Synthesis and evaluation of isoprenylation-resveratrol dimer derivatives against Alzheimer's disease' [Eur. J. Med. Chem. 163 (2019), 307-319. DOI: 10.1016/j.ejmech.2018.11.040]

Yan-Wei Tang, Cun-Jian Shi, Hua-Li Yang, Pei Cai, Qiao-Hong Liu, Xue-Lian Yang, Ling-Yi Kong, Xiao-Bing Wang

Eur J Med Chem. 2024 Sep 5:275:116591. doi: 10.1016/j.ejmech.2024.116591.

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