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In this issue we highlight a selection of most recently introduced Reactive Intermediates containing moropholine,piperazine,piperiainemorpholine,piperazine,piperidine and pyrrolidine groups.
The solubilizing and hydrogen-bonding propertied of the compounds feature here make them ideal for use in lead potimisation programmes,.They are just a small subset of over 500similar compounds in our collection ,and illustrate our continuing commitment to developing the ultimate toolbox of medchem-relevant building blocks.  
 
CAS
英文名称
分子式
结构式
4-(4-isocyanatopyrid-2-yl)morpholine
 
C10 H11 N3 O2
4-(6-isocyanatopyrid-2-yl)morpholine
C10 H11 N3 O2
6-morpholinopyridine-2-carbaldehyde
C10 H12 N2 O2
3-(morpholinomethyl)benzaldehyde
 
C12 H15 N O2
2-(2-morpholinoethoxy)benzaldehyde
 
C13 H17 N O3
 
3-(2-morpholin-4-ylethoxy)benzaldehyde
C13 H17 N O3
2-morpholinoisonicotinaldehyde
C10 H12 N2 O2
6-morpholinopyridine-2-carboxylic acid
C10 H12 N2 O3
5-morpholinothiophene-2-carboxylic acid
C9 H11 N O3 S
[2-(morpholin-4-ylmethyl)-1H-benzimidazol-1-yl]acetic acid
C14 H17 N3 O3
(6-morpholinopyrid-2-yl)methylamine
C10 H15 N3 O
(2-morpholinopyrid-4-yl)methylamine
 
C10 H15 N3 O
1-[2-(morpholin-4-ylmethyl)phenyl]methanamine
C12 H18 N2 O
N-methyl-N-[(6-morpholin-4-ylpyridin-2-yl)methyl]amine
C11 H17 N3 O
 
N-methyl-N-[2-(morpholin-4-ylmethyl)benzyl]amine
C13 H20 N2 O
2-(morpholin-4-ylmethyl)aniline
 
C11 H16 N2 O
4-[6-(tributylstannyl)-2-pyridinyl]morpholine
C21 H38 N2 O Sn
4-[2-(2-bromophenoxy)ethyl]morpholine
 
C12 H16 Br N O2
4-(3-iodobenzyl)morpholine
C11 H14 I N O
4-(2-iodobenzyl)morpholine
 
C11 H14 I N O
[3-(2-morpholinoethoxy)phenyl]methanol
C13 H19 N O3
(2-morpholinopyrid-4-yl)methanol
C10 H14 N2 O2
tert-butyl 4-(5-formylpyrid-2-yl)piperazine-1-carboxylate
C15 H21 N3 O3
3-[(4-methylpiperazin-1-yl)methyl]benzaldehyde
C13 H18 N2 O
4-[(4-methylpiperazin-1-yl)methyl]benzaldehyde
C13 H18 N2 O
4-[(4-methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride 0.5 hydrate
C13 H18 N2 O2 . 2 H Cl . 0.5 H2 O
{2-[(4-methylpiperazin-1-yl)methyl]phenyl}methylamine
C13 H21 N3
2-methyl-6-piperazin-1-ylpyrazine
 
C9 H14 N4
3-(4-methylpiperazin-1-yl)aniline
C11 H17 N3
13339-02-1
2-Piperazin-1-ylaniline
C10 H15 N3
 
2-[(4-methylpiperazin-1-yl)methyl]aniline
 
C12 H19 N3
7-chloro-4-piperazinoquinoline
C13 H14 Cl N3
tert-butyl 4-(5-iodopyrid-2-yl)piperazine-1-carboxylate
C14 H20 I N3 O2
1-(3-iodobenzyl)-4-methylpiperazine
C12 H17 I N2
1-(4-iodobenzyl)-4-methylpiperazine
C12 H17 I N2
1-(2-iodobenzyl)-4-methylpiperazine
C12 H17 I N2
tert-butyl 4-[5-(hydroxymethyl)pyrid-2-yl]piperazine-1-carboxylate
C15 H23 N3 O3
{3-[(4-methylpiperazin-1-yl)methyl]phenyl}methanol
C13 H20 N2 O
{2-[(4-methylpiperazin-1-yl)methyl]phenyl}methanol
C13 H20 N2 O
4-allyl 1-(9-H-fluoren-9-ylmethyl) hydrogen piperazine-1,2,4-tricarboxylate
 
C24 H24 N2 O6
1-(tert-butoxycarbonyl)-4-[(9H-fluoren-9-ylmethoxy)carbonyl]-2-piperazinecarboxylic acid
C25 H28 N2 O6
4-(tert-butoxycarbonyl)-1-[(9H-fluoren-9-ylmethoxy)carbonyl]-2-piperazinecarboxylic acid
 
C25 H28 N2 O6
9H-fluoren-9-ylmethyl 4-(3-butenoyl)tetrahydro-1(2H)-pyrazinecarboxylate
C23 H24 N2 O3
1-(4-isocyanatophenyl)piperidine
 
C12 H14 N2 O
1-(4-isocyanatobenzyl)piperidine
C13 H16 N2 O
3-(piperidinomethyl)benzaldehyde
C13 H17 N O
6-piperidin-1-ylnicotinaldehyde
 
C11 H14 N2 O
6-piperidinopyridine-2-carboxylic acid
 
C11 H14 N2 O2
3-(piperidinomethyl)benzoic acid hydrochloride hemihydrate
 
C13 H17 N O2 . H Cl . 0.5 H2 O
(6-piperidinopyrid-2-yl)methylamine
C11 H17 N3
benzyl 4-[(methylamino)methyl]piperidine-1-carboxylate
C15 H22 N2 O2
tert-butyl 4-{4-[(methylamino)methyl]-1,3-thiazol-2-yl}piperidine-1-carboxylate
 
C15 H25 N3 O2 S
tert-butyl 4-(4-fluorobenzoyl)piperidine-1-carboxylate
C17 H22 F N O3
benzyl 4-(aminomethyl)tetrahydro-1(2H)-pyridinecarboxylate
C14 H20 N2 O2
1-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]piperidine
C18 H28 B N O2
1-(3-iodobenzyl)piperidine
C12 H16 I N
1-(4-iodobenzyl)piperidine
C12 H16 I N
tert-butyl 4-[4-(hydroxymethyl)-1,3-thiazol-2-yl]piperidine-1-carboxylate
C14 H22 N2 O3 S
(6-piperidinopyrid-2-yl)methanol
C11 H16 N2 O
[3-(piperidinomethyl)phenyl]methanol
C13 H19 N O
6-pyrrolidin-1-ylpyridine-2-carbaldehyde
 
C10 H12 N2 O
2-pyrrolidin-1-ylbenzaldehyde
 
C11 H13 N O
2-pyrrolidin-1-ylisonicotinaldehyde
C10 H12 N2 O
4-(pyrrolidin-1-ylmethyl)benzaldehyde
C12 H15 N O
2-pyrrolidin-1-ylisonicotinic acid, 1.5 hydrate
 
C10 H12 N2 O2 . 1.5 H2 O
4-(pyrrolidin-1-ylmethyl)benzoic acid
C12 H15 N O2
(2-pyrrolidin-1-ylphenyl)methylamine
C11 H16 N2
(2-pyrrolidin-1-ylpyrid-4-yl)methylamine
C10 H15 N3
4-(pyrrolidin-1-ylmethyl)benzylamine
C12 H18 N2
2-pyrrolidin-1-ylaniline
C10 H14 N2
3-(pyrrolidin-1-ylmethyl)aniline
C11 H16 N2
N-methyl-N-(4-pyrrolidin-1-ylbenzyl)amine
 
C12 H18 N2
N-methyl-N-(3-pyrrolidin-1-ylbenzyl)amine
C12 H18 N2
N-methyl-2-pyrrolidin-1-ylbenzylamine
C12 H18 N2
N-methyl-N-[(2-pyrrolidin-1-ylpyridin-4-yl)methyl]amine
C11 H17 N3
(2-pyrrolidin-1-ylphenyl)methanol
C11 H15 N O
[4-(pyrrolidin-1-ylmethyl)phenyl]methanol
C12 H17 N O
1-(4-bromophenyl)pyrrolidine
C10 H12 Br N
2-bromo-6-pyrrolidin-1-ylpyridine
C9 H11 Br N2
1-(3-bromophenyl)pyrrolidine
C10 H12 Br N
1-(4-iodobenzyl)pyrrolidine
C11 H14 I N
1-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyrrolidine
 
C16 H24 B N O2
8-benzyl-8-azabicyclo[3.2.1]octan-3-one
C14 H17 N O
(2S)-1-tert-butyl hydrogen 4-oxopyrrolidine-1,2-dicarboxylate
C10 H15 N O5
 
 
 

 

 

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